Delbès, Géraldine PhD - Regular researcher


Professor - Centre INRS–Institut Armand-Frappier

INRS–Institut Armand-Frappier

Research interest

Our research projects aim to determine how exposition to medical or environmental compounds, during specific sensitive periods of the life cycle, can affect male fertility. Epidemiologic data suggest a worldwide increase in male fertility problems associated to a decrease of sperm production, an increase in the incidence of testicular cancer and developmental abnormalities in the development of the male reproductive tract in human and many wildlife species. Data demonstrating a negative impact of exposition to chemical compounds found in the environment or used for medical procedures on the male reproductive function are accumulating. However, the cellular and molecular mechanisms involved on these impacts on male fertility are poorly documented. We are working on the characterization of these mechanisms in immature germinal cells, spermatogenesis precursors. Using rodent and human in vivo and in vitro models, we study gene expression in the programming of germinal cells, in response to the chemical environment.  

 

Expertise

Gonocytes Epigenetics Perinatal life Male fertility Endocrine disruptors

Centre INRS–Institut Armand-Frappier

Pavillon de la Recherche et de la Formation
Édifice 18
531 boulevard des Prairies,
Laval (QC) Canada
H7V 1B7
(450) 687-5010 extension : 8830
Fax : (450) 686-5501
geraldine.delbes@iaf.inrs.ca

Postdoctoral fellowship: Department of Phamacology and Therapeutics, McGill University (Montreal, Qc, Canada  )

PhD: Reproduction et Développement, Université paris Sud (Paris, France)

MSc:  DEA de Physiologie de la Reproduction à l’Université Pierre et Marie Currie (Paris, France)

Undergraduate: Biologie Cellulaire et Physiologie à l’Université Denis Diderot (Paris, France)


Direction
Tardif, Sarah - Master - Studies in progress
Subject :

Recherche de substituts sécuritaires aux perturbateurs endocriniens



codirection
Dubuc, Karine - Master - Studies in progress
Subject :

Étude de l’établissement du réseau de communication entre l’ovocyte et le cumulus  

Direction
Rwigemera, Arlette - PhD - Studies in progress
Subject :

Étude in vitro de l’effet des xénoestrogènes sur la reprogrammation épigénétique dans les cellules germinales foetales du rat mâle

Elomri, Rhizlane - PhD - Studies in progress



1 Latest projects

  • Analyse ciblée de la méthylation d'ADN dans la lignée germinale mâle pour le dépistage de l'influence environnementale