Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA.


  • Date de publication : 2015-07-08

Référence

Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannée C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Lévesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E. Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA. Proc. Natl. Acad. Sci. U.S.A. 2015;112:E3564-73. doi: 10.1073/pnas.1507905112. PubMed PMID: 26106157.

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12-hydroxy-5,8,10,14-eicosatetraenoic acid animals arachidonate 12-lipoxygenase arthritis, experimental arthritis, rheumatoid blood platelets cell line cell-derived microparticles cells, cultured endocytosis group ii phospholipases a2 humans immunoblotting mice, inbred c57bl mice, knockout mice, transgenic microscopy, confocal microscopy, electron mitochondria neutrophils rna reverse transcriptase polymerase chain reaction synovial fluid

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