Beyond Fertilisation: How the Paternal Environment Influences Future Generations

  • Date de publication : 2020-05-17


Janice L Bailey, Mathieu Dalvai, Maryse Lessard, Pauline M Herst, Phanie L Charest, P Navarro. Beyond Fertilisation: How the Paternal Environment Influences Future Generations. 
Anim Reprod Sci. 2020 May 17;106503. doi: 10.1016/j.anireprosci.2020.106503. PMID: 32536524 DOI: 10.1016/j.anireprosci.2020.106503 

Mot(s) Clé(s)

epigenomics folic acid sperm


In light of the relatively ignored role of paternal influences on offspring development and increasing societal concerns regarding possible health consequences of chemical exposures, our team has addressed the overall hypothesis that environmentally-relevant levels of contaminants have long-lasting effects that are transmitted through the paternal lineage. This review focuses on our research examining the impact of developmental exposure to toxicants and nutrients on the phenotype and epigenome of the male and of his subsequent generations. This report is intended to encourage animal andrologists as well as the domestic animal production industry to increase their consideration of the sire's environment in the context of agricultural productivity.