Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH.


  • Date de publication : 1998-05-04

Référence

Acampora D, Mazan S, Tuorto F, Avantaggiato V, Tremblay JJ, Lazzaro D, di Carlo A, Mariano A, Macchia PE, Corte G, Macchia V, Drouin J, Brûlet P, Simeone A. Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH. Development. 1998;125:1229-39. PubMed PMID: 9477321.

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Mot(s) Clé(s)

animals body constitution dwarfism female follicle stimulating hormone gene expression regulation, developmental growth hormone homeodomain proteins hypogonadism hypothalamus immunohistochemistry luteinizing hormone male mice mice, knockout nerve tissue proteins otx transcription factors pituitary gland promoter regions, genetic rna, messenger receptors, lhrh receptors, somatotropin transcription factors

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