CHARGE syndrome-associated proteins FAM172A and CHD7 influence male sex determination and differentiation through transcriptional and alternative splicing mechanisms
Identification of novel genes and pathways regulated by the orphan nuclear receptor COUP-TFII in mouse MA-10 Leydig cells
The Nuclear Receptor COUP-TFII Regulates Amhr2 Gene Transcription via a GC-Rich Promoter Element in Mouse Leydig Cells.
In vivo ablation of the conserved GATA binding motif in the Amh promoter impairs Amh expression in the male mouse.
Phosphorylation of GATA4 serine 105 but not serine 261 is required for testosterone production in the male mouse.
Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesis.
GATA4 knockdown in MA-10 Leydig cells identifies multiple target genes in the steroidogenic pathway.
GATA4 autoregulates its own expression in mouse gonadal cells via its distal 1b promoter.
Transgenic mouse analysis of Sry expression during the pre- and peri-implantation stage.
An Ebox element in the proximal Gata4 promoter is required for Gata4 expression in vivo.
Functional cooperation between GATA factors and cJUN on the star promoter in MA-10 Leydig cells.
Sertoli cell behaviors in developing testis cords and postnatal seminiferous tubules of the mouse.
Conserved usage of alternative 5' untranslated exons of the GATA4 gene.
The expression of the nuclear receptors NR5A1 and NR5A2 and transcription factor GATA6 correlates with steroidogenic gene expression in the bovine corpus luteum.
The effect of human GATA4 gene mutations on the activity of target gonadal promoters.
A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation.
Novel pre- and post-gastrulation expression of Gata4 within cells of the inner cell mass and migratory neural crest cells.
Role of the GATA family of transcription factors in endocrine development, function, and disease.
GATA factors and the nuclear receptors, steroidogenic factor 1/liver receptor homolog 1, are key mutual partners in the regulation of the human 3beta-hydroxysteroid dehydrogenase type 2 promoter.
New insights into the regulation of mammalian sex determination and male sex differentiation.